个人简介
北京大学yl6809永利官网博士,美国莱斯大学博士后,主持国家自然科学基金青年项目,北理工青年教师学术启动计划和yl6809永利官网科技创新计划科研基地科技支撑专项计划。在国内外学术刊物上发表学术论文30余篇,包括J. Am. Chem. Soc., Chem. Sci.等。
研究领域和方向
我的研究兴趣主要集中在化学与生命科学的交叉领域,旨在通过发展化学工具探测和调节生命过程,揭示生物事件的发生发展规律,为疾病的治疗提供新思路。包括:1)发展低能量光可活化荧光探针监测细胞通讯动力学;2)发展阴离子配体靶向性治疗癌症;3)发展不含重金属的光敏剂用于癌症的光动力治疗。
教育背景
2012.09-2017.07 北京大学,化学专业,理学博士 2008.09-2012.07 武汉大学,药学专业,理学学士
工作履历
2020.12至今 yl6809永利官网,预聘副教授,博士生导师 2017.08-2020.06 美国莱斯大学,化学院,博士后研究员
研究成果
迄今在国内外学术刊物及会议上发表学术论文30篇,其中SCI收录26篇,EI收录14篇,两项美国专利正在审批,代表性论文如下: (1)Juan Tang, # Michael Robichaux, # Kuan-Lin Wu, Jingqi Pei, Nhung T. Nguyen, Yubin Zhou, Theodore G. Wensel*, and Han Xiao*, Single-Atom Fluorescence Switch: A General Approach towards Visible Light-Activated Dyes for Biological Imaging, J. Am. Chem. Soc., 2019, 141, 37, 14699 (# contributed equally). Highlighted by JACS Spotlight [Link], and C&EN [Link]. Featured in Rice News [Link], and ScienceDaily [Link] (2)Juan Tang, # Lushun Wang, # Axel Loredo, Carson Cole, and Han Xiao*, Single-Atom Replacement as a General Approach Towards Visible-Light/Near-Infrared Heavy-Atom-Free Photosensitizers for Photodynamic Therapy, Chem. Sci., 2020, 11, 6701 (# contributed equally). Included in 2020 Chemical Science HOT Article Collection [Link], Featured in Rice News [Link] Phys.org [Link] (3)Juan Tang, # Chenfei Yu, Axel Loredo, Yuda Chen, and Han Xiao*, Site-Specific Incorporation of a Photoactivatable Fluorescent Amino Acid, ChemBioChem, 2020, 22, 501 (4)Juan Tang, Hao-Yan Yin, Jun-Long Zhang*, A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells, Chem. Sci., 2018, 9, 1931 (5)Juan Tang, Yuan-Bo Cai, Jing Jing and Jun-Long Zhang*, Unravelling the Correlation between Metal Induced Aggregation and Cellular Uptake/Subcellular Localization of Znsalen: An Overlooked Rule for Design of Luminescent Metal Probes, Chem. Sci., 2015, 6, 238